TABLE 1.
Baseline demographics and clinical characteristics for the endoscopic lung volume reduction (ELVR) group and the no-ELVR group
| ELVR group | No-ELVR group | p-value | |
| Subjects n | 20 | 18 | |
| Age years | 65±6 | 63±5 | 0.18 |
| Female | 45 | 67 | 0.21¶¶ |
| BMI kg·m−2 | 23±3 | 22±4 | 0.43 |
| Emphysema score at −910 HU# | 71±8 | 69±7 | 0.44 |
| Heterogeneity index¶ | 19±12 | 21±11 | 0.60 |
| GOLD stage IV | 55 | 50 | >0.99¶¶ |
| FEV1 L | 0.79±0.22 | 0.83±0.25 | 0.69 |
| FEV1 % pred | 32±8 | 33±8 | 0.61 |
| FRC % pred | 192±19 | 211±39 | 0.07 |
| TLC % pred | 128±12 | 140±21 | 0.04 |
| RV % pred | 222±31 | 235±51 | 0.35 |
| 6MWD m | 356±74 | 380±58 | 0.27 |
| SGRQ total score+ | 61±12 | 63±16 | 0.70 |
| mMRC dyspnoea scoreƒ | 3±0.6 | 3±0.7 | 0.43++ |
| BODE index score## | 5±1 | 5±1 | 0.32++ |
Data are presented as mean±sd or %, unless otherwise stated. BMI: body mass index; GOLD: Global Initiative for Chronic Obstructive Lung Disease; FEV1: forced expiratory volume in 1 s; FRC: functional residual capacity; TLC: total lung capacity; RV: residual volume; 6MWD: 6-min walk distance; SGRQ: St George's Respiratory Questionnaire; mMRC: modified Medical Research Council; BODE: BMI, airflow obstruction, dyspnoea, exercise capacity. #: emphysema destruction score of the target lobe was assessed as the percentage of voxels <−910 HU on computed tomography; ¶: difference in emphysema score between the target lobe and the ipsilateral lobe; +: score range from 0 to 100, with lower score indicating better quality of life; ƒ: scale ranges from 0 to 4, with higher scores indicating more severe symptoms of dyspnoea; ##: score ranges from 0 to 10, with higher scores indicating larger mortality risk. p-values obtained by two-sample t-test, unless otherwise stated. ¶¶: Fisher's exact test; ++: Wilcoxon rank sum test.