TABLE 5.
Within-group difference for mean absolute changes of lung volume reduction surgery (LVRS) from baseline to 6-month follow-up in secondary outcome measures
| LVRS | Δ LVRS 6-month follow-up | p-value | ||
| Baseline | 6 months | |||
| Subjects | 16 | 14 | ||
| FEV1 L | 0.78±0.07 | 1.05±0.07 | 0.27±0.06 | 0.0001 |
| RV L | 5.37±0.26 | 3.88±0.27 | −1.49±0.22 | <0.0001 |
| RV % pred | 256±11 | 186±12 | −70±10 | <0.0001 |
| FRC L | 6.62±0.30 | 5.37±0.32 | −1.25 ±0.24 | <0.0001 |
| TLC L | 8.01±0.33 | 7.00±0.35 | −1.01±0.25 | 0.0005 |
| 6MWD m | 365±17 | 439±18 | 75±18 | 0.0003 |
| SGRQ total score | 56±4 | 38±4 | −18±4 | <0.0001 |
| BODE index score | 5±0.4 | 2.9±0.4 | −2±0.4 | <0.0001 |
| mMRC dyspnoea score | 2.7±0.2 | 1.2±0.2 | −1.5±0.3 | <0.0001 |
Data are presented as n or mean±sem, unless otherwise stated. FEV1: forced expiratory volume in 1 s; RV: residual volume; FRC: functional residual capacity; TLC: total lung capacity; 6MWD: 6-min walk distance; SGRQ: St George's Respiratory Questionnaire; BODE: body mass index, airflow obstruction, dyspnoea, exercise capacity; mMRC: modified Medical Research Council.