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. 2021 May 17;12:680073. doi: 10.3389/fimmu.2021.680073

Figure 2.

Figure 2

Effects of L. casei on inflammatory responses in rats. The levels of IL-1β (A), TNFα (B), IL-6 (C) and IL-10 (D) in plasma were determined by ELISA. The percentage of Treg cells (E) and Th17 cells (F) in MLN were determined by flow cytometry. control (vehicle-treated with saline 1.5 mL/day) group, CIA (vehicle-treated with saline 1.5 mL/day) group, methotrexate (MTX)-treated (6 mg/kg/week) group, CCFM1074 (treated with CCFM1074, 8.5 × 109 CFU/day) group and CCFM1075 (treated with CCFM1075, 8.5 × 109 CFU/day) group, eight rats per group. *p<0.05, **p<0.01 (one-way ANOVA test with Tukey’s multiple comparisons test).