Table 1.
Clinical data and pregnancy outcomes in different protocols.
| Variables | GnRH-a (n = 3,104) | GnRH-ant (n = 1,527) | P |
|---|---|---|---|
| Age (y) | 30.00 (6.00) | 31.00 (8.00) | <0.05 |
| Infertility duration (mo) | 36.00 (36.00 | 38.00 (48.00) | <0.05 |
| Number of gravidities | 2.00 (1.00) | 1.00 (1.00) | <0.05 |
| BMI (kg/m(2)) | 23.08 (3.36) | 23.68 (3.59) | <0.05 |
| bFSH (mIU/mL) | 7.13 (2.42) | 7.62 (3.34) | <0.05 |
| bE2 (pg/mL) | 37.00 (28.00) | 39.00 (28.48) | <0.05 |
| bP (ng/mL) | 0.66 (0.55) | 0.64 (0.51) | <0.05 |
| bLH (mIU/mL) | 4.11 (2.44) | 4.05 (2.72) | >0.05 |
| bT (ng/mL) | 0.42 (0.25) | 0.41 (0.26) | >0.05 |
| bAMH (ng/mL) | 2.71 (2.12) | 1.81 (2.25) | >0.05 |
| Total dose of Gn (IU) | 2400 (975) | 2400 (1050) | >0.05 |
| EMT (mm) | 10.00 (2.00) | 11.00 (2.00) | <0.05 |
| Endometrial echo type | |||
| A | 63.0% (1955/3104) | 65.0% (993/1527) | >0.05 |
| B | 35.4% (1099/3104) | 32.6% (498/1527) | >0.05 |
| C | 1.6% (50/3104) | 2.4% (36/1527) | >0.05 |
| Number of embryos transferred | |||
| 1 | 5.3% (165/3104) | 11.4% (173/1527) | <0.05 |
| 2 | 93.2% (2892/3104) | 83.4% (1274/1527) | <0.05 |
| 3 | 1.5% (47/3104) | 5.2% (80/1527) | <0.05 |
| Clinical pregnancy rate | 64.7% (2008/3104) | 66.9% (1022/1527) | >0.05 |
| Live birth rate | 54.9% (1705/3104) | 53.8% (821/1527) | >0.05 |
| Miscarriage rate | 13.0% (262/2008) | 15.9% (163/1022) | <0.05 |
GnRH-a, gonadotropin-releasing hormone agonist; GnRH-ant, gonadotropin-releasing hormone antagonist; mo, month; BMI, body mass index; bFSH, basal follicle-stimulating hormone; bE, baseline estradiol; bP, baseline progesterone; bLH, baseline luteinizing hormone; bT, baseline testosterone; bAMH, baseline anti-Mullerian hormone; EMT, Endometrial thickness.