Table 4.
Clinical data and pregnancy outcomes in subgroups of GnRH-ant protocol.
| Variables | G1 | G2 | G3 | P |
|---|---|---|---|---|
| N | 76 | 741 | 595 | |
| Age (y) | 31.00 (7.00) | 32.00 (7.00) | 31.00 (7.00) | <0.05 |
| Infertility duration (mo) | 36.00 (48.00) | 36.00 (42.00) | 41.50 (48.00) | >0.05 |
| BMI (kg/m2) | 23.59 (4.28) | 23.05 (4.59) | 23.40 (4.56) | >0.05 |
| Number of gravidities | 1.00 (2.00) | 1.00 (2.00) | 0.00 (1.00) | <0.05 |
| bFSH (mIU/ml) | 7.80 (4.32) | 7.67 (3.52) | 7.56 (3.14) | >0.05 |
| bE2 (pg/ml) | 45.50 (28.25) | 40.00 (29.00) | 38.00 (29.00) | >0.05 |
| bP (ng/ml) | 0.65 (0.71) | 0.68 (0.53) | 0.61 (0.48) | <0.05 |
| bLH (mIU/ml) | 3.90 (2.23) | 4.05 (2.74) | 4.21 (2.81) | >0.05 |
| bT (ng/ml) | 0.37 (0.18) | 0.43 (0.13) | 0.40 (0.27) | <0.05 |
| bAMH (ng/ml) | 0.96 (0.71) | 1.52 (1.64) | 2.20 (3.07) | <0.05 |
| Total dose of Gn(IU) | 2100.00 (675.00) | 2400.00 (975.00) | 2400.00 (1125.00) | <0.05 |
| Total dose of GnRH-ant(mg) | 0.50 (0.50) | 0.50 (0.63) | 0.63 (0.62) | <0.05 |
| Number of embryos transferred | ||||
| 1 | 26.32% (20/76) | 12.96% (96/741) | 11.43% (68/595) | >0.05 |
| 2 | 71.05% (54/76) | 81.11% (601/741) | 83.53% (497/595) | >0.05 |
| 3 | 2.63% (2/76) | 5.94% (44/741) | 5.04% (30/595) | >0.05 |
| Endometrial echo type | ||||
| A | 60.5% (46/76) | 67.7% (502/741) | 64.0% (381/595) | >0.05 |
| B | 38.2% (29/76) | 30.5% (226/741) | 34.3% (204/595) | >0.05 |
| C | 1.3% (1/76) | 1.8% (13/741) | 1.7% (10/595) | >0.05 |
| Clinical pregnancy rate | 56.58% (43/76) a | 61.81% (458/741) a | 70.59% (420/595) b | <0.05 |
| Live birth rate | 44.74% (34/76) a | 49.80% (369/741) a | 61.01% (363/595) b | <0.05 |
| Miscarriage rate | 20.93% (9/43) | 19.43% (89/458) | 13.57% (57/420) | >0.05 |
GnRH-ant, gonadotropin-releasing hormone antagonist; mo, month; BMI, body mass index; bFSH, basal follicle-stimulating hormone; bE2, baseline estradiol; bP, baseline progesterone; bLH, baseline luteinizing hormone; bT, baseline testosterone; bAMH, baseline anti-Mullerian hormone. Identical subscript letters indicate no significant difference while different subscript letters significant (P < 0.05) difference. Group G1, endometrial thickness ≤7.0 mm; Group G2, endometrial thickness belongs to 7.0–10.0 mm; Group G3, endometrial thickness >10.0 mm.