Table 1.
Study | Mechanism of Action for HDL's Anti-inflammatory Properties |
---|---|
Kimura et al.36 | Inhibition of key cell adhesion molecules, including VCAM-1 and ICAM-1 |
Yuhanna et al.64 | Stimulating eNOS and production of nitric oxide |
Bursill et al.37 | Suppressing endothelial cell chemokine expression (CCL2, CCL5, and CX3CL1) |
Murphy et al.10 | Decreasing the expression of monocyte CD11b in a dose-dependent manner |
Sanson et al.43 | Promoting the transition of M1-like macrophages to M2-like macrophages |
Liu et al.44 | Inhibition of inflammatory cytokine production from monocytes |
eNOS, endothelial nitric oxide synthase; HDL, high-density lipoproteins.