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. 2021 May 26;10(7):370–380. doi: 10.1089/wound.2020.1308

Table 1.

Anti-inflammatory effects of high-density lipoproteins

Study Mechanism of Action for HDL's Anti-inflammatory Properties
Kimura et al.36 Inhibition of key cell adhesion molecules, including VCAM-1 and ICAM-1
Yuhanna et al.64 Stimulating eNOS and production of nitric oxide
Bursill et al.37 Suppressing endothelial cell chemokine expression (CCL2, CCL5, and CX3CL1)
Murphy et al.10 Decreasing the expression of monocyte CD11b in a dose-dependent manner
Sanson et al.43 Promoting the transition of M1-like macrophages to M2-like macrophages
Liu et al.44 Inhibition of inflammatory cytokine production from monocytes

eNOS, endothelial nitric oxide synthase; HDL, high-density lipoproteins.