Skip to main content
. 2021 May 26;38(12):1702–1716. doi: 10.1089/neu.2020.7309

FIG. 11.

FIG. 11.

ASC-CCM alleviates glutamate induced gliosis through actions on glutamate-aspartate transporter (GLAST) in Müller glia. (A) The schematic diagram of GLAST transfection in the rMC-1 cells. The rMC-1 cells were transfected with a GLAST small interfering RNA (siRNA) or a scrambled control siRNA (siCON). Assessment of gene expression by TaqMan quantitative polymerase chain reaction (qPCR)and expressed as fold change normalized to internal control (glyceraldehyde 3-phosphate dehydrogenase). (B) GLAST (***p < 0.001; *p < 0.03), (C) glial fibrillary acidic protein (GFAP; ***p < 0.001) and (D) glutamine synthetase (GS; *p < 0.04). # denotes p > 0.05. Data represent mean ± standard error of the mean (SEM) from n = 3 independent assessments /group. Color image is available online.