Table 1.

Comparison of the complementary estimates of the homologous RBD_Spike bound binary PPI complexes

PDB ID	SPIKE RBD source	Strain	ACE2	Sc	EC	CSl	Pcount	Nlsp	Nimp
3D0G	2002–2003 SARS-CoV	Human	Human-civet chimeric	0.168	−0.648	−6.56	58.3	0	4
3D0H	2002–2003 SARS-CoV	Civet*	Human-civet chimeric	0.211	−0.445	−1.92	47.1	2	5
3SCL	SARS-CoV	Epidemic	Human-civet chimeric	0.382	0.034	1.18	22.9	6	5
3SCJ	Predicted SARS-CoV	Civet	Human	0.523	0.301	1.45	20.0	7	0
2AJF	SARS-CoV	Human	Human	0.417	0.185	1.09	23.5	5	3
6VW1	SARS-COV-2 COVID-19	Chimeric	Human	0.555	0.102	1.15	14.7	5	3

In the table, P_count refers to the percentage of interfacial residues falling in the “improbable” regions of the plot. N_lsp and N_imp refer to numbers of interfacial residues falling, respectively, in the “less probable” and “improbable” regions of the residue-wise Complementarity Plot (CP_int; see the “Complementarity Plot (CP_int and CP_dock)” section)

*Paguma larvata