Table 1.
Study population description
| Variable | N=73 (%) |
|---|---|
| Age (in years, mean ± standard deviation) | 38.9 ± 11.9 |
| Sex | |
| Male | 27 (37) |
| Female | 46 (63) |
| Race | |
| American Indian or Alaska Native | 1 (1) |
| Black or African American | 66 (91) |
| White | 4 (5) |
| Not provided | 2 (3) |
| Sickle Cell Genotype | |
| HbSS | 59 (81) |
| HbSC | 9 (12) |
| HbSBO | 2 (3) |
| HbSB+ | 3 (4) |
| Hair cortisol content (pg/mg, mean± standard deviation) | 17.1 ± 41.6 |
| Ferritin Level | |
| Mean (µg/L) | 1384 |
| Median (µg/L) | 629 |
| Range (µg/L) | 18-10948 |
| Over 1000 mcg/L | 26 (36) |
| Less than 1000 mcg/L | 47 (64) |
| Self-reported Iron Overload | |
| Present | 23 (32) |
| Absent | 49 (67) |
| Unavailable | 1 (1) |
| On Chronic Transfusion Program | |
| Yes | 14 (19) |
| No | 59 (81) |
| Eosinophil Level (% ± standard deviation) | 3.0 ± 2.2 |
| Hemoglobin S (% ± standard deviation) | 67.6 ± 20.0 |
The population used in this study included all individuals from the Insights into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study or INSIGHTS (NCT02156102) who provided a hair sample as of August 2018. All individuals have sickle cell disease.