Table 3.

Reticulocyte parameters showing sensitivity, specificity, AUC and cut off values in IDA, Alpha/Beta Thalassemia and Dual positive (IDA + Alpha Thalassemia) patients

Reticulocyte parameter	Iron deficiency Anemia	Alpha Thalassemia	Beta Thalassemia	Dual positive patients (IDA + Alpha Thalassemia)
Reticulocyte count (RET)	Sensitivity = 54.1%	Sensitivity = 54.5%	Sensitivity = 63.8%	NA
	Specificity = 58%	Specificity = 77.2%	Specificity = 78.5%
	AUC = 0.58	AUC = 0.69	AUC = 0.75
	Cut-off = 1.54	Cut-off = 1.67	Cut-off = 2.06
Immature Reticulocyte Fraction (IRF)	Sensitivity = 59.4%	Sensitivity = 54.5%	Sensitivity = 65.2%	Sensitivity = 51.9%
	Specificity = 50.2%	Specificity = 70.7%	Specificity = 64.5%	Specificity = 55.3%
	AUC = 0.54	AUC = 0.66	AUC = 0.68	AUC = 0.48
	Cut-off = 15.15	Cut-off = 18	Cut-off = 19.7	Cut-off = 16.75
Reticulocyte hemoglobin content (RET-HE)	Sensitivity = 68.3%	Sensitivity = 46.2%	Sensitivity = 46.4%	Sensitivity = 74.2%
	Specificity = 62.9%	Specificity = 62.9%	Specificity = 61%	Specificity = 57.4%
	AUC = 0.69	AUC = 0.56	AUC = 0.51	AUC = 0.7
	Cut-off = 22.25	Cut-off = 23.85	Cut-off = 22.15	Cut-off = 21.25