Table 2.
Comparative analysis of Clinical and Hematological parameters in subcategories of COVID-19 patients based on disease severity
| Very severe (n=51) | Severe (n=118) | Moderate (n=337) | p value | |
|---|---|---|---|---|
| Age | 64.06±11.05 | 52.38±14.86 | 35.3±11.8 | - |
| M:F ratio | 3.25:1 | 2.37:1 | 1.39:1 | - |
| Mortality | 60.8% | 1.7% | 0% | - |
| Hb | 12.01±2.20 | 11.58±2.03 | 11.5±2.39 | 0.526* |
| Hct | 38.95±6.78 | 33.73±6.19 | 37.3±7.27 | 0.350* |
| RBC | 4.3±0.91 | 4.19±1.21 | 4.16±0.89 | 0.630** |
| MCV | 91.86±6.88 | 89.64±14.17 | 90.24±12.02 | 0.806* |
| MCH | 28.4±3.9 | 28.43±3 | 27.96±3.43 | 0.555* |
| MCHC | 30.96±1.53 | 31.03±1.55 | 30.7±1.56 | 0.151* |
| RDW SD | 56.31±8.09 | 52.55±6.7 | 51.78±7.8 | <0.0001** |
| RDW CV | 16.19±2.51 | 15.75±2.88 | 15.30±2.63 | 0.076* |
| WBC | 16.75±11.93 | 12.05±7.39 | 9.74±6.76 | <0.0001* |
| ANC | 12.31±7.24 | 9.4±6.69 | 6.79±5.54 | <0.0001* |
| ALC | 2.53±5.31 | 1.79±2.08 | 1.89±1.2 | <0.0001* |
| AMC | 0.93±0.85 | 0.76±0.59 | 0.65±0.56 | 0.001* |
| AEC | 0.1±0.19 | 0.19±0.22 | 0.16±0.28 | <0.0001* |
| NLR | 19.58±27 | 17.36±22.56 | 7.43±30.02 | <0.0001* |
| PLR | 260.71±290.65 | 234.38±242 | 149.42±272 | <0.0001* |
| MLR | 0.96±1.33 | 0.66±0.53 | 0.49±1.18 | <0.0001* |
| PLATELET | 212.9±97.16 | 218±124 | 183±99.88 | 0.007* |
| PDW | 17.43±3.78 | 16.24±3.51 | 15.99±3.6 | 0.012* |
| MPV | 12.55±1.2 | 12.22±1.24 | 12.09±1.3 | 0.050** |
| PLCR | 42.94±8.93 | 41.67±8.8 | 41.12±9.48 | 0.406** |
| PCT | 0.23±0.08 | 0.23±0.07 | 0.24±0.089 | 0.278** |
| ESR | 29.56±5.42 | 24.34±5.86 | 22.8±5.87 | <0.0001** |
*
Kruskal Wallis test;
**
ANOVA;
p value less than 0.05 is considered statistically significant.
The continuous variables in the three groups viz., moderate, severe and very severe were subjected to test of normality. The non normally distributed variables in three groups (Moderate, Severe and Very severe) were compared using Kruskal Walis test and normally distributed variables were analysed using ANOVA test.