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. 2021 Apr 15;11(2):180–190.

Table 5.

Area under the curve for various hematological parameters in severe and very severe versus moderate COVID-19 patients

Variable Area under curve p value 95% Confidence Interval

Lower Bound Upper Bound
WBC .662 .000 .610 .713
RDWSD .535 .203 .483 .587
RDWCV .549 .070 .495 .603
NLR .676 <0.0001 .623 .728
PLR .654 <0.0001 .600 .707
MLR .654 <0.0001 .601 .707
NLR and RDWSD .861 <0.0001 .825 .897
NLR and RDWCV .871 <0.0001 .838 .904
NLR and PLR .859 <0.0001 .823 .896
NLR and MLR .858 <0.0001 .821 .894

The severe and very severe cases were taken as primary outcome for calculating area under the curve (AUC) for parameters. A new variable was generated by combining two parameters along with age and sex and were then subjected to binary logistic regression model with severity as outcome. The new variable was generated in form of predicted probability from the model.