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. 2021 May 17;12:688508. doi: 10.3389/fphar.2021.688508

FIGURE 1.

FIGURE 1

(A) Chemical structures of glycyrrhizin (GL, 5) and its metabolites (14), 18β-glycyrrhetyl-3-O-glucuronide (3MGA, 6), and glycyrrhetinic acid (GA, 7) (B) Key two-dimensional (2D) nuclear magnetic resonance (NMR) correlations for 4 (C) Selected rotating frame overhause effect spectroscopy (ROESY) correlations and relative stereochemistry of 4.