Table 4.
Candidate genes in the selection regions and their functions
| Gene symbol | Location (Mb) | Full name | Function of association |
|---|---|---|---|
| FGF10 | 13.97–14.03 | Fibroblast growth factor 10 | Promotes fat formation [22] |
| IL6ST | 17.02–17.06 | Interleukin 6 signal transducer | Increases fat oxidation and fatty acid re-esterification [25]. |
| ELOVL7 | 18.87–18.91 | ELOVL fatty acid elongase 7 | Extension of saturated fatty acids [26] |
| IQGAP2 | 23.46–23.58 | IQ motif containing GTPase activating protein 2 | Influences the liver uptake of free fatty acids, fatty acid synthesis and adipogenesis [27] |
| CKMT2 | 63.95–63.98 | Creatine kinase, mitochondrial 2 | Regulation of energy metabolism, expression in brown adipose tissue [28] |
| PAX5 | 82.01–82.12 | Paired box 5 | Regulates obesity [29] |