Table 3.

Multivariate analysis of the association between clinical variables and patient survival.

Variable	HR (95% CI)	Statistical significance
Tumour number (multiple versus single)	2.03 (0.83, 2.57)	NS
Tumour size (>5 versus ≤5 cm)	1.98 (1.13, 2.74)	NS
Tumour differentiation (well versus moderate versus poor)	2.58 (1.93, 3.64)	P = 0.042
TNM stage (III–IV versus I–II)	3.21 (2.67, 4.26)	P = 0.029
Lymph node metastasis (yes or no)	2.24 (1.43, 3.27)	NS
PRC1 in tumour tissue (high or low)	0.27 (1.58, 4.74)	P = 0.016

TNM, tumour node metastasis; PRC1, protein regulator of cytokinesis 1; HR, hazard ratio; CI, confidence interval.

NS, no statistically significant association (P > 0.05).