Table 4.

Association between PRC1 levels and clinical characteristics in 45 patients with cholangiocarcinoma

	Expression of PRC1 in tumour tissue
Characteristic	Low	High	Statistical significance
Patients (n = 45)	32	13	P < 0.0001
Sex
Male (n = 23)	16	7	P < 0.05
Female (n = 22)	16	6	P < 0.05
Age
>58 years	18	5	P < 0.001
≤58 years	14	8	P < 0.05
CA 19-9 (ng/ml)
≤37	28	10	P < 0.05
>37	4	3	NS
γ-GGT (U/l)
≤50	30	11	P < 0.05
>50	2	2	NS
Tumour number
Single	31	1	P < 0.0001
Multiple	1	12	P < 0.0001
Tumour size (cm)
≤5	29	2	P < 0.001
>5	3	11	P < 0.05
Tumour differentiation (degree)
Well differentiated	2	3	NS
Moderate differentiated	29	6	P < 0.001
Poor differentiated	1	4	P < 0.05
TNM stage (I–IV)
I–II (n = 32)	26	6	P < 0.001
III–IV (n = 13)	6	7	NS
Lymph node metastasis
Positive	32	13	P < 0.005
Negative	0	0	NS

Data presented as n prevalence.

CA 19-9, carbohydrate antigen 19-9; γ-GGT, γ- glutamyl transferase; PRC1, protein regulator of cytokinesis 1.

NS, no statistically significant correlation (P > 0.05).