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. 2021 Mar 26;49(3):0300060521996564. doi: 10.1177/0300060521996564

Figure 4.

Figure 4.

circPPP1CC alleviated the inhibitory effect of miR-107 and miR-103a-3p on HMGB1 expression. (a) Predicted binding sites between HMGB1 and miR-107 or miR-103a-3p. (b) Luciferase activity determined between HMGB1 and miR-107 or miR-103a-3p. **P < 0.01, ***P < 0.001; error bars represent standard deviation.

circPPP1CC, circular RNA serine/threonine-protein phosphatase PP1-gamma catalytic subunit; HMGB1, high mobility group box 1; NC, negative control; wt, wild type; mut, mutant.