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The distribution of mean infarct differences for conservative treatment patients between final diffusion-weighted imaging (DWI) infarct with predicted (a) computed tomography perfusion plus (CTP+), (b) RAPID, (c) Sphere, and (d) Vitrea infarct. Dashed lines represent the 90th percentile of volume differences. Note the extended tail into the negative volume difference region for RAPID and Sphere, indicating overestimation of penumbra.
