Fig. 5.

Comparison of the predicted missing response values using ML-CDN2 and the existed response values for two types of inhibitors. a Comparison of predicted missing and available observed IC₅₀ values for EGFR mutant and wild-type cell lines for which experimental IC₅₀ values were missing from the GDSC dataset for EGFR inhibitors, including afatinib, cetuximab, erlotinib, gefitinib and lapatinib. b Comparison of predicted missing and available observed IC₅₀ values for BRAF mutant and wildtype cell lines for which experimental IC₅₀ values were missing in the GDSC dataset for three MEK inhibitors, including AZD6244, RDEA119 and PD-0325901