Table 2.

Univariate and multivariate analysis of different parameters for overall survival in CRC patients

Variables	Univariate analysis		Multivariate analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Gender (male vs female)	0.881 (0.526–1.477)	0.632
Age (≥ 67 vs < 67)	1.929 (1.135–3.281)	0.015*	1.318 (0.749–2.318)	0.338
pT status (T3-T4 vs T1-T2)	7.270 (2.635–20.057)	< 0.001***	3.004 (1.004–8.989)	0.049*
pN status (N1-N2 vs N0)	7.164 (4.201–12.217)	< 0.0001****	2.690 (1.429–5.065)	0.0022**
pM status (M1 vs M0)	15.165 (8.692–26.456)	< 0.0001****	6.337 (3.387–11.859)	< 0.0001****
Histological grade (G3 vs G1-G2)	0.594 (0.335–1.054)	0.075	1.144 (0.620–2.109)	0.667
Recurrence (YES vs NO)	1.752 (0.701–4.382)	0.230
GOLT1B expression (High vs Low)	5.089 (2.189–11.834)	< 0.001***	2.520 (1.034–6.142)	0.042*

Univariate and multivariate Cox proportional hazards regression were used to calculate Hazard ratio (HR), 95% confidence intervals (95% CI) and p values in SPSS 24.0. Low GOLT1B is defined as IHC score < 5 and High GOLT1B is defined as IHC score ≥ 5. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001