Skip to main content
. 2021 May 17;13:658605. doi: 10.3389/fnagi.2021.658605
Groups Gender (Male) Age (yrs) ApoE4 allele carrier Last MMSE score NIA-R (High) Neuritic plaque (C3) NFT stage (B3) TMT 10 PLEX LABELS
Young controls (N = 9) 56% (5/9) 47 ± 3.3 67% (6/9) N/A N/A N/A N/A −126, −127N, −128C
Aged controls (N = 15) 60% (9/15) 87.4 ± 1.5 20% (3/15) 28.1 ± 0.5 0% (0/15) 0% (0/15) 0% (0/15) −126, −127N, −127C*, −128N
Low CAA Score (≤4) [AD] (N = 10) 30% (3/10) 85.5 ± 2.9 40% (4/10) 16.7 ± 2.4 50% (5/10) 60% (6/10) 50% (5/10) −129C,−130N, −130C, −131
High CAA Score (≥8) [AD] (N = 10) 40% (4/10) 81 ± 4.4 60% (6/10) 14 ± 3.3 90% (9/10) 100% (10/10) 90% (9/10) −129N, −129C,−130N, −130C, −131

Cx, Cortex; ADNC, Alzheimer's disease neuropathological change; NIA-R, National institute of Aging Regan Diagnosis of AD.