Table 2.
Odds ratio for the presence of interstitial lung disease, simple logistic regression
| Total cohort | Confirmed RA subgroup | Unconfirmed RA subgroup | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Odds ratio | p value | 95% CI | Odds ratio | p value | 95% CI | Odds ratio | p value | 95% CI | |||
| Age | 1.06 | < 0.01 | 1.04–1.08 | 1.04 | < 0.01 | 1.01–1.07 | 1.06 | < 0.01 | 1.04–1.09 | ||
| Tobacco | 2.23 | < 0.01 | 1.35–3.68 | 3.7 | < 0.01 | 1.62–8.45 | 1.4 | 0.35 | 0.70–2.79 | ||
| CRP | 1.01 | 0.17 | 1.0–1.02 | 1 | 0.79 | 0.99–1.02 | 1.01 | 0.38 | 0.99–1.03 | ||
| RA | 3.38 | < 0.01 | 1.98–5.78 | Not applicable | Not applicable | ||||||
| Male gender* | 0.86 | 0.65 | 0.46–1.62 | 1.07 | 0.9 | 0.39–2.90 | 0.7 | 0.4 | 0.31–1.60 | ||
| Asian, Hispanic, and Native Hawaiian races** | 0.94 | 0.94 | 0.22–3.99 | 1.12 | 0.92 | 0.14–9.01 | 0.86 | 0.88 | 0.11–6.48 | ||
| African American race** | 1.04 | 0.92 | 0.48–2.25 | 0.95 | 0.93 | 0.34–2.67 | 0.82 | 0.75 | 0.24–2.78 | ||
| Other or not stated race** | 1.21 | 0.61 | 0.58–2.54 | 0.98 | 0.97 | 0.32–3.01 | 1.31 | 0.56 | 0.49–3.53 | ||
| Anti-CCP 6–150 U/mL compared to anti-CCP 0–5 U/mL | 2.59 | 0.01 | 1.21–5.52 | 1.51 | 0.48 | 0.48–4.74 | 1.59 | 0.65 | 0.21–12.07 | ||
| anti-CCP 150–300 U/mL compared to anti-CCP 0—5 U/mL | 4.64 | 0.02 | 1.35–15.93 | 2.61 | 0.21 | 0.59–11.47 | † | ||||
| anti-CCP >300 U/mL compared to anti-CCP 0–5 U/mL | 5.43 | < 0.01 | 2.77–10.64 | 2.83 | 0.06 | 0.96–8.39 | 6.38 | 0.02 | 1.41–28.90 | ||
*
Compared to female gender
**
Compared to Caucasian race
†
Of two patients in this category, neither developed ILD