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. 2021 May 17;10:577229. doi: 10.3389/fonc.2020.577229

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Copyright © 2021 Chen, Song, Nie, Lin, Yu, Kong, Qi and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Silencing CXCL1 inhibits cell proliferation, migration, invasion and promotes cell apoptosis of CRC. (A) qRT-PCR results showed the relative expression of CXCL1 after sh-CXCL1 and sh-NC were respectively transfected into SW837 and SW480 cells, (B) CCK-8, (C) wound healing assay, (D) Transwell invasion assay (100×), and (E) flow cytometry results showed the effect of silenced CXCL1 on proliferation, migration, invasion, and apoptosis of transfected cells (*p < 0.05).