Table 1.
Basic characteristics of the 203 patients with EAL and Determinants of EAL postoperative overall healing in patients with EAL.
| Factors | No. of patients | Univariate | Multivariate | ||
|---|---|---|---|---|---|
| (N=203) | P value | HR | 95% CI | P value | |
| Diagnosis and treatment procedure | <0.001 | ||||
| conventional management a | 94 | ||||
| endoscopic diagnosis | 87 | 1.67 | 1.20-2.32 | 0.002 | |
| systematic endoscopic intervention | 22 | 2.81 | 1.70-4.63 | <0.001 | |
| Sex (male vs. female) | 167/36 | 0.734 | |||
| Age (year) (<62 vs. ≥62) | 102/101 | 0.818 | |||
| Body mass index (kg/m2) (<22 vs. ≥22) | 108/95 | 0.846 | |||
| ASA PS (II vs. III) | 151/52 | 0.663 | |||
| Smoking index(package*years)(<25 vs. ≥25) | 101/102 | 0.325 | |||
| Drinking history (yes vs. no) | 69/134 | 0.949 | |||
| Diabetes Mellitus (yes vs. no) | 23/180 | 0.120 | |||
| Hypertension (yes vs. no) | 52/151 | 0.171 | |||
| Gastric ulcer and/or gastritis (yes vs. no) | 144/59 | 0.485 | |||
| Tumor location (upper vs. middle vs. lower thoracic) | 21/124/58 | 0.074 | |||
| Tumor staging (I vs. II vs. III vs. IV) | 44/62/87/10 | 0.113 | |||
| Minimally invasive surgery (yes vs. no a ) | 65/138 | 0.003 | 1.55 | 1.11-2.15 | 0.009 |
| Postoperative fever (yes vs. no) | 60/143 | 0.112 | |||
| Neo-adjuvant therapy (yes vs. no) | 30/173 | 0.846 | |||
| Leak location (cervical vs. intrathoracic) | 123/80 | 0.686 | |||
HR, Hazard ratio; 95% CI, 95% confidence interval; ASA PS, American Society of Anesthesiologists classification of physical status.
a
Reference category.
Bold values means the difference was statistically significant.