Fig. 2.

Steps of segmentation for (a) cortical bone (CB55, 55% of length) layers from periosteum to endosteum to obtain TMD (b) mean, (c) SD, (d) Low5, and (e) High5. The OVX group had significantly lower values of all TMD parameters at each distance compared to the sham group (p<0.046), except SD between 350 μm and 540 μm, and Low5 between 675 μm and 810 μm (p>0.051).