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. 2021 May 17;11:642144. doi: 10.3389/fonc.2021.642144

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Copyright © 2021 Chen, Liu, Lu, He, Zhang and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TIC profiles of tumor samples from OS patients and correlation analyses. (A) The proportions of 22 types of TICs among the tumor samples from OS patients are shown in the bar chart. Sample IDs are used as the names of column. (B) The correlations among the 22 types of TICs in the different OS samples are indicated in the heatmap with the p values (number in each box) of the correlations between two cells shown. The corresponding correlation values (shade of each colored box) are displayed, and significance was evaluated using the Pearson correlation coefficient. (C–E) The differences in 22 kinds of TICs between the high and low C1qA, C1qB and C1qC expression groups are shown in the violin plot. The Wilcoxon rank-sum was applied to test significance. The TIC names are shown on the X-axis, and the contents are indicated on the Y-axis.