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. 2021 May 17;14:665931. doi: 10.3389/fnmol.2021.665931

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Copyright © 2021 Wu, Yang, Ou, Chen, Huang, Xiong, Sun and Xiao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A mass number of DEGs were induced by VZV in SH-SY5Y cells. (A) Volcanic map showed the number and distribution of DEGs in SH-SY5Y cells after 24 h of VZV infection. (B) Volcanic map showed the number and distribution of DEGs in SH-SY5Y cells after 48 h of VZV infection. Volcano map showed that VZV group had significant mRNA expression compared with mock without VZV infection. Log₂ (Fold change) and log₁₀ (Q-value) of DEGs are expressed as abscissa and ordinate, respectively. The significantly upregulated genes are shown in red and the significantly downregulated genes are shown in green.