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. 2021 May 17;12:651105. doi: 10.3389/fphys.2021.651105

FIGURE 5.

FIGURE 5

Changes in the activation of IRE1α, TRAF2, ASK1, JNK, and caspase-12 in the IRE1α receptor-related pathway signaling pathway in DM mice. (A) Representative protein expression bands of IRE1α, TRAF2, ASK1, JNK, and caspase-12. (B) Representative Western blot analysis of p-IRE1α/IRE1α. (C) Representative Western blot analysis of caspase-12. (D) Representative Western blot analysis of TRAF2. (E) Representative Western blot analysis of p-ASK1/ASK1. (F) Representative Western blot analysis of p-JNK/JNK. Tukey’s post hoc test for one-way ANOVA was used to analyze the Western blot immunocontent. For each group, n = 6. The vertical lines represent the standard error of the mean. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.