Figure 2.
mtDNAT414G/total mtDNA ratio analysis in different ocular structures. Total DNA was harvested from the cornea, iris and neural retina isolated from 7 human subjects. The mtDNAT414G/total mtDNA ratio was derived from each ocular structure by Q-PCR. A higher mtDNAT414G level has been found in the iris (0.051%), when compared to the cornea (0.021%) and the neural retina (0.012%). According to Wilcoxon matched-paired rank test, the mtDNAT414G/total mtDNA ratio was significantly different between the iris and the cornea and between the iris and the neural retina (*P value < 0.02) but not between the cornea and the neural retina.
