Table 2.
Comparison of clinical variables between all treated patients and TMB-evaluable patients
| Characteristic | All treated patients N = 270 |
TMB-evaluable patients n = 139 |
|---|---|---|
| Mean age (range), years | 65.0 (38–90) | 64.5 (38–85) |
| Age group, % | ||
| <65 years | 45.2 | 45.3 |
| ≥65 and <75 years | 40.7 | 42.4 |
| ≥75 years | 14.1 | 12.2 |
| Sex, % | ||
| Male | 78.1 | 78.4 |
| Female | 21.9 | 21.6 |
| Baseline hemoglobin (g/dL), % | ||
| <10 | 17.8 | 18.0 |
| ≥10 | 82.2 | 82.0 |
| Liver metastases, % | ||
| Yes | 28.9 | 33.1 |
| No | 70.4 | 66.9 |
| Not reported | 0.7 | – |
| Visceral metastases, % | ||
| Yes | 82.6 | 80.6 |
| No | 16.7 | 19.4 |
| Not reported | 0.7 | – |
| Lymph node–only metastases, % | ||
| Yes | 16.7 | 19.4 |
| No | 82.6 | 80.6 |
| Not reported | 0.7 | – |
| PD-L1 expression, % | ||
| <1% | 54.1 | 49.6 |
| ≥1% | 45.9 | 50.4 |
| TMB classification by tertiles, % | ||
| High | – | 33.8 |
| Medium | – | 33.1 |
| Low | – | 33.1 |