Table 1.
Demographic and clinical data of the study population. Values expressed in percentages (%) indicate the proportion of patients within each cohort for each variable. Data are presented as median with interquartile ranges (IQR) where specified. SIMD: sepsis-induced myocardial dysfunction; BMI: body mass index; BP: blood pressure; CRP: c-reactive protein; PCT: procalcitonin; APACHE: Acute Physiology: Age and Chronic Health Evaluation; SOFA: Sequential Organ Failure Assessment; NT-proBNP: N-terminal pro-b-type natriuretic peptide; hs-TnI: high-sensitivity troponin I; CK-MB: creatine kinase-MB; Lcn10: lipocalin 10. ∗P < 0.05.
| Variables | Non-SIMD (n = 40) | SIMD (n = 35) | P value |
|---|---|---|---|
| Age (y), median (IQR) | 62.5 (55.3-68.8) | 58.0 (53.0-67.0) | 0.189 |
| Gender, male, n (%) | 20 (50%) | 21 (60%) | 0.386 |
| BMI (kg/m2), median (IQR) | 22.0 (20.0-25.75) | 20.0 (19.0-22.0) | 0.071 |
| Hospital length of stay (days), median (IQR) | 7 (5-12) | 7 (6-11) | 0.905 |
| Death before day 28, n (%) | 4 (10%) | 11 (31.4%) | 0.021∗ |
| Systolic BP (mmHg), median (IQR) | 97 (86-119) | 90 (80-97) | 0.046∗ |
| Diastolic BP (mmHg), median (IQR) | 54 (44-64) | 52 (45-62) | 0.864 |
| Heart rate (beat/min), median (IQR) | 91 (82-110) | 93 (84-112) | 0.381 |
| Lactate (mmol/L), median (IQR) | 1.225 (0.890-2.175) | 3.760 (2.330-5.890) | <0.001∗ |
| CRP (mg/L), median (IQR) | 149 (99-203) | 156 (89-244) | 0.737 |
| PCT (ng/mL), median (IQR) | 4.76 (1.27-15.30) | 9.43 (2.18-79.34) | 0.359 |
| APACHE II score, median (IQR) | 17 (13-22) | 21 (15-26) | 0.015∗ |
| SOFA score, median (IQR) | 7 (5-10) | 11 (9-14) | <0.001∗ |
| NT-proBNP (pg/mL), median (IQR) | 442 (208-2129) | 983 (534-2310) | 0.053 |
| hs-TnI (ng/mL), median (IQR) | 0.328 (0.151-1.854) | 1.030 (0.540-2.780) | 0.004∗ |
| CK-MB (ng/mL), median (IQR) | 5.74 (3.19-12.07) | 11.71 (3.08-19.65) | 0.350 |
| Myoglobin (μg/L), median (IQR) | 154 (89-347) | 207 (144-456) | 0.057 |