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. Author manuscript; available in PMC: 2021 Sep 29.
Published in final edited form as: Biometrics. 2020 Aug 25;77(3):1024–1036. doi: 10.1111/biom.13356

Table 1.

Simulation results (all the entries are multiplied by 100) under Setting 1. PL, the standard Cox regression with the partial likelihood; DEL and DEL-E, the double empirical likelihood method and its extension by Huang et al. (2016); ADEL, the proposed adaptive double empirical likelihood method.

PC Method β 1 β2
Bias SD SE RMSE CP RE Bias SD SE RMSE CP RE
Sample Size=100
0% PL −1.27 11.09 11.56 11.15 95.4 1.93 21.69 21.25 21.76 95.4
DEL −0.68 4.92 4.90 4.96 95.4 0.44 −0.76 17.62 17.48 17.62 94.8 0.81
DEL-E −0.80 5.02 4.96 5.08 95.0 0.46 1.61 21.07 21.02 21.11 95.4 0.97
ADEL −1.29 9.65 8.73 9.73 95.0 0.87 0.72 18.96 18.91 18.96 94.6 0.87
15% PL −1.53 12.28 12.43 12.36 95.2 1.17 26.29 23.05 26.29 92.0
DEL −0.31 5.03 4.87 5.04 95.2 0.41 −0.95 20.33 18.72 20.33 92.4 0.77
DEL-E −0.38 5.07 4.91 5.08 95.2 0.41 0.72 25.95 22.80 25.93 92.0 0.99
ADEL −1.65 10.68 9.67 10.80 96.6 0.87 0.33 22.42 20.55 22.40 93.0 0.85
30% PL −1.97 13.27 13.68 13.40 95.4 2.11 29.04 25.44 29.08 92.2
DEL −0.32 5.09 4.94 5.10 95.0 0.38 −0.80 21.44 20.20 21.43 92.8 0.74
DEL-E −0.41 5.14 4.98 5.15 95.6 0.38 1.51 28.67 25.15 28.68 91.8 0.99
ADEL −2.04 11.34 10.90 11.51 96.6 0.86 0.84 23.35 22.81 23.34 93.8 0.80
Sample Size=200
0% PL −0.18 8.15 8.00 8.15 95.4 0.44 15.17 14.78 15.16 95.2
DEL −0.35 3.48 3.44 3.49 94.4 0.43 −1.09 12.50 12.26 12.54 95.2 0.83
DEL-E −0.42 3.51 3.47 3.53 94.0 0.43 0.23 14.92 14.68 14.91 94.6 0.98
ADEL −0.44 7.19 6.29 7.20 93.8 0.88 −0.28 13.52 13.06 13.51 94.8 0.89
15% PL −1.10 8.87 8.66 8.92 95.0 −0.76 15.84 15.99 15.84 94.2
DEL −0.39 3.53 3.51 3.55 95.0 0.40 −1.05 12.59 13.14 12.62 95.2 0.80
DEL-E −0.39 3.53 3.52 3.55 94.8 0.40 −1.17 15.62 15.88 15.65 95.0 0.99
ADEL −1.17 7.98 6.89 8.05 94.2 0.90 −0.54 13.85 14.14 13.85 95.0 0.87
30% PL −1.12 9.60 9.49 9.66 95.4 −0.71 18.11 17.59 18.11 93.6
DEL −0.37 3.60 3.56 3.61 95.8 0.37 −1.22 14.25 14.17 14.28 94.4 0.79
DEL-E −0.38 3.61 3.57 3.62 95.4 0.37 −1.17 17.86 17.47 17.88 93.4 0.99
ADEL −1.09 8.73 7.10 8.80 94.6 0.91 −0.65 15.91 15.50 15.91 94.8 0.88