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. Author manuscript; available in PMC: 2021 Sep 29.
Published in final edited form as: Biometrics. 2020 Aug 25;77(3):1024–1036. doi: 10.1111/biom.13356

Table 4.

Simulation results (all the entries are multiplied by 100) under Setting 4. PL, the standard Cox regression with the partial likelihood; DEL and DEL-E, the double empirical likelihood method and its extension by Huang et al. (2016); ADEL, the proposed adaptive double empirical likelihood method.

PC Method β 1 β 2
Bias SD SE RMSE CP RE Bias SD SE RMSE CP RE
Sample Size=100
0% PL −1.27 11.09 11.56 11.15 95.4 1.93 21.69 21.25 21.76 95.4
DEL 7.36 4.30 4.29 8.52 55.8 0.76 −15.73 16.18 16.97 22.55 87.8 1.04
DEL-E 6.81 4.50 4.42 8.16 59.8 0.73 0.30 20.72 20.98 20.70 96.4 0.95
ADEL −1.68 10.79 10.82 10.91 92.2 0.98 −3.27 19.48 20.43 19.73 95.8 0.91
15% PL −1.53 12.28 12.43 12.36 95.2 1.17 26.29 23.05 26.29 92.0
DEL 7.84 4.34 4.23 8.95 51.8 0.72 −16.65 18.64 18.17 24.98 85.2 0.95
DEL-E 7.40 4.45 4.33 8.64 56.0 0.70 −0.48 25.46 22.76 25.44 92.6 0.97
ADEL −2.04 11.71 11.78 11.87 93.2 0.96 −3.41 22.61 22.32 22.85 94.4 0.87
30% PL −1.97 13.27 13.69 13.40 95.4 2.11 29.04 25.44 29.08 92.2
DEL 7.94 4.36 4.25 9.06 49.6 0.68 −17.62 19.67 19.62 26.40 86.6 0.91
DEL-E 7.55 4.47 4.35 8.77 54.0 0.65 0.37 28.00 25.11 27.98 92.4 0.96
ADEL −2.39 12.44 13.11 12.66 95.0 0.94 −2.92 23.70 24.63 23.85 95.6 0.82
Sample Size=200
0% PL −0.18 8.15 8.00 8.15 95.4 0.44 15.17 14.78 15.16 95.2
DEL 7.62 3.04 3.01 8.20 30.2 1.01 −15.91 11.44 11.90 19.60 73.0 1.29
DEL-E 7.13 3.12 3.09 7.78 37.2 0.95 −1.05 14.57 14.65 14.60 96.0 0.96
ADEL −0.95 8.12 7.82 8.17 92.0 1.00 −4.12 13.78 14.48 14.37 94.8 0.95
15% PL −1.10 8.87 8.66 8.92 95.0 −0.76 15.84 15.99 15.84 94.2
DEL 7.74 3.04 3.04 8.31 28.4 0.93 −16.52 11.54 12.75 20.15 78.6 1.27
DEL-E 7.35 3.10 3.10 7.97 33.2 0.89 −2.25 15.29 15.86 15.44 95.2 0.97
ADEL −1.71 8.77 8.42 8.93 91.8 1.00 −4.88 14.15 15.57 14.95 94.4 0.94
30% PL −1.12 9.60 9.49 9.66 95.4 −0.71 18.11 17.59 18.11 93.6
DEL 7.88 3.09 3.06 8.46 26.2 0.88 −17.70 13.14 13.76 22.04 78.4 1.22
DEL-E 7.53 3.14 3.12 8.15 30.2 0.84 −2.18 17.51 17.45 17.63 94.8 0.97
ADEL −1.79 9.37 9.20 9.53 92.6 0.99 −4.92 16.08 17.12 16.80 94.6 0.93