Table 2.
Viral-derived sequences sharing sequence homology with tumor-associated antigens (TAAs)
| HLA-A*0201 | |||||
| Mutation | Tumor specific | ||||
| VVMSWAPPV | NWMSWVLPI | Envelope protein (HERV-H/env59) | MLAVISCAV | MLAVISTIR | Envelope glycoprotein UL33 (human betaherpesvirus 7) |
| GLFGDIYLA | GLFNDIYPN | Envelope glycoprotein, partial (HIV 1) | FLWGPRALV | SQWGPRAIL | Deoxyuridine triphosphatase (human alphaherpesvirus 2) |
| LLDDLLVSI | CSDDLLISI | DNA packaging terminase subunit 1 (human betaherpesvirus 7) | KVAELVHFL | KVAELRQFL | Pol protein, partial (HIV 1) |
| ILDKVLVHL | ILEKVHVHL | Major capsid protein, partial (human papillomavirus) | KASEKIFYV | HEEEKVFYV | E2 protein (human papillomavirus 77) |
| ILDCVLVHL | E1 protein (human papillomavirus) | KVVEFLAML | KVVEFLSGS | Capsid maturation protease (human betaherpesvirus 5) | |
| FLIIWQNTM | LDIIWQNMT | Envelope glycoprotein (HIV 1) | |||
| RLSSCVPVA | AVSTCVPVA | Envelope glycoprotein B (human alphaherpesvirus 2) | |||
| Differentiation | Overexpressed | ||||
| IMIGVLVGV | IMVGALIGV | Envelope glycoprotein, partial (HIV 1) | RLMNDMTAV | RLADDMTSV | Large tegument protein (human alphaherpesvirus 2) |
| IIIGALVGV | Envelope glycoprotein (HIV 1) | RLAPFVYLL | RLAPFGYKI | Polyprotein, partial (Vilyuisk human encephalomyelitis virus) | |
| IMIGGLIGL | Envelope glycoprotein (HIV 1) | FLLGLIFLL | PLLGLIFLS | Polymerase (human T-lymphotropic virus 4) | |
| RLMKQDFSV | NEMKQDFVV | Major capsid protein (human betaherpesvirus 5) | LLNAFTVTV | LLNAFAITV | Envelope glycoprotein (HIV 1) |
| YMDGTMSQV | YMNSTMSET | Structural protein VP7 (human rotavirus A) | KKNAFTVTV | Early protein E2 (human papillomavirus 157) | |
| MLGTHTMEV | MLGTHAMLV | Membrane protein UL20 (human betaherpesvirus 5) | LLNAFAIAV | Envelope glycoprotein (HIV 1) | |
| MLLAVLYCL | NLLAVLYCV | Gag protein, partial (HIV 1) | FLGYLILGV | AVGYLILGV | CR1-alpha (human adenovirus 42) |
| NTLAVLYCV | Gag protein (HIV 1) | RLVDDFLLV | RLVDEFLAI | Envelope glycoprotein (HIV 1) | |
| KTWGQYWQV | DTWGEYWQA | Pol protein, partial (HIV 1) | RLVNDFLAL | Envelope glycoprotein (HIV 1) | |
| TWWGEYWQA | Pol protein, partial (HIV 1) | SLLSGDWVL | TDESGDWVL | Envelope glycoprotein, partial (HIV 1) | |
| YLSGANLNL | YLSGANMLY | Hexon protein (human adenovirus 46) | ALLALTSAV | ALLPLTSAN | Polyprotein, partial (human poliovirus 2) |
| GDDKILDTV | Polyprotein (human enterovirus 79) | ALLALTKAQ | Outer capsid glycoprotein VP7, partial (human rotavirus A) | ||
| SLSKILDTV | SMTKILDTF | Pol protein, partial (HIV 1) | ALWPWLLMA | CLWPWLAIE | Envelope protein UL43 (human gammaherpesvirus 4), vpr protein (HIV 1) |
| TLMSAMTNL | CLMPAMTNN | UL86 (human betaherpesvirus 5) | VSWPWLLRW | Hypothetical protein (human alphaherpesvirus 2) | |
| LLWSFQTSA | SPWSFQTLT | Envelope glycoprotein (HIV 1) | TVLIWLLMA | Envelope glycoprotein (HIV 1) | |
| FLFLLFFWL | FLFMLYFWN | Protein UL140 (human betaherpesvirus 5) | LLGRNSFEV | LLGRNSFRG | Envelope glycoprotein (HIV 1) |
| IVTLLFFLF | Protein UL140 (human betaherpesvirus 5) | LLGRNSWEA | Envelope glycoprotein (HIV 1) | ||
| YLEPGPVTA | TLEPGPVVR | L2 (human papillomavirus type 54) | KIFGSLAFL | KIFGSLVYF | L2 protein (human papillomavirus) |
| LLEPGPPTA | LF1 (human gammaherpesvirus 4) | TLPGYPPHV | DALGYPPHV | EBNA-3A (human gammaherpesvirus 4) | |
| VLHWDPETV | ALHWDPSIG | Unknown, partial (human picobirnavirus) | SPQHYPPHV | Capsid maturation protease (human alphaherpesvirus 1) | |
| LLLLTVLTV | LLLNTVLTV | ORF46 (human gammaherpesvirus 8) | |||
| CQWGRLWQL | DEWASLWXW | Envelope glycoprotein, partial (HIV 1) | |||
| FLALSILVL | YLALSVLVT | Vif protein (HIV 1) | |||
| FLALSIVNR | Envelope glycoprotein (HIV 1) | ||||
| RLLQETELV | RLLQQTEVY | E6 (human papillomavirus type 39) | |||
| LLLQETEVI | Envelope glycoprotein, partial (HIV 1) | ||||
| ILHNGAYSL | ILXNGXYSL | Truncated pol protein, partial (HIV 1) | |||
| ILXNGQYSL | |||||
| YYHNGAYSD | Envelope glycoprotein (HIV 1) | ||||
| VLVPPLPSL | DQVPPLPSL | Gag protein, partial (HIV 1) | |||
| KEIPPLPSL | Gag protein, partial (HIV 1) | ||||
| DREPPLPSL | Gag protein (HIV 1) | ||||
| LLSDDDVVV | SLAEDDVVV | Envelope glycoprotein, partial (HIV 1) | |||
| KMDAEHPEL | RMDAEHPGL | Polymerase PB1 (influenza B virus) | |||
| KMDEEHPGL | Polymerase PB1 (influenza B virus (B/Ann Arbor/1994)) | ||||
| VFDPEHPEL | DNA polymerase (human mastadenovirus D, human adenovirus 63) | ||||
| CIAEQYHTV | SAAEAYHTV | Small hydrophobic protein (human metapneumovirus) | |||
| HLSTAFARV | LLSTAFARW | Protein UL150 (human betaherpesvirus 5) | |||
| LLSTAFAIW | Protein UL150 (human betaherpesvirus 5) | ||||
| TIHDSIQYV | QIHDRIQYV | BALF5 (human gammaherpesvirus 4) | |||
| KVHPVIWSL | SVHPVLWNC | ORF4a protein (human betacoronavirus 2c Jordan-N3/2012) | |||
| MIMVKCWMI | TQEVKCWMT | p24, partial (HIV 1) | |||
| MIMVKGIPK | Envelope glycoprotein O (human betaherpesvirus 5) | ||||
| MIMVKVGGQ | Pol protein, partial (HIV 1) | ||||
| DIMVKCYLA | DNA polymerase (human mastadenovirus C) | ||||
| HLA-A24:02 | |||||
| Mutation | Tumor specific | ||||
| TAA | Blast Seq | Virus | TAA | Blast Seq | Virus |
| SYLDSGIHF | TYLDNGVHV | L2 protein human papillomavirus 204 | NYKRCFPVI | NYKKCYPKI | Human rotavirus A |
| Differentiation | Overexpressed | ||||
| TAA | Blast Seq | Virus | TAA | Blast Seq | Virus |
| N/A | NYARTEDFF | LYKRTEDFW | Reverse transcriptase, partial (HIV 1) | ||
| HLA-A01:01 | |||||
| Mutation | Tumor specific | ||||
| TAA | Blast Seq | Virus | TAA | Blast Seq | Virus |
| YVDFREYEY | ETMFREYNY | Envelope glycoprotein B (HHV-8) | N/A | ||
| Differentiation | Overexpressed | ||||
| TAA | Blast Seq | Virus | TAA | Blast Seq | Virus |
| N/A | N/A | ||||
| HLA-A03:01 | |||||
| Mutation | Tumor specific | ||||
| TAA | Blast Seq | Virus | TAA | Blast Seq | Virus |
| N/A | SLFRAVITK | SLFNAVVTL | Gag polyprotein, HIV 1 | ||
| Differentiation | Overexpressed | ||||
| TAA | Blast Seq | Virus | TAA | Blast Seq | Virus |
| ALNFPGSQK | ALNFPGKWK | Pol polyprotein, HIV 1 | LASFKSFLK | LAAFKSFLK | E1 protein human papillomavirus 57 |