Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 31;7:69. doi: 10.1038/s41523-021-00259-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — a Left: representative images of anchorage-independent growth patterns of controls versus SUM159 cells stably expressing human SOCS5. Right: ImageJ quantitation of colony numbers in Left displayed as mean ± SD of n = 5. b Growth kinetics of indicated orthotopic tumors derived from SUM159 controls (n = 12) or SUM159 cells expressing pLVX-SOCS5 (n = 9) in Nu/Nu nude mice measured by digital calipers with mean ± SD indicated per time point. c Weight of the indicated SUM159 tumors in B with the median shown. d Left: representative images of immunohistochemistry of Ki67 in tumor tissues in c; Right: quantitation of Ki67 positive cells in Left displayed as box-and-whisker plots representing the median (centerline) and inter-quartile range (IQR; box). The whiskers extend up to 1.5 times the IQR from the box to the smallest and largest points. e Left: representative images of anchorage-independent growth patterns of Hs578T cells stably expressing sh scramble control, shSOCS5#1 and shSOCS5#4. Right: ImageJ quantitation of colony numbers in Left displayed as mean ± SD of n > 3. f Left: representative images of anchorage-independent growth patterns of controls versus SUM159 cells stably expressing SOCS5 shRNA#4. Right: ImageJ quantitation of colony numbers in Left displayed as mean ± SD of n > 3. g Left: representative images of anchorage-independent growth patterns of controls versus SOCS5 shRNA#4 in CAL51 cells. Right: ImageJ quantitation of colony numbers in Left displayed as mean ± SD of n > 3. h Proliferation (mean ± SD of n = 3) of control or LINC01119-over-expressing SUM159 cells transfected with esiRLUC or esiSOCS5 measured using CellTiter after 72 h.