Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Oxygenation within the liver. The oxygen gradient decreases in blood as it travels through the hepatic sinusoids (Zone 1) toward the pericentral region (Zone 3), significantly altering the local microenvironment and influencing immune cell localization and activity. Kupffer cells are larger and more numerous in periportal zones than in perivenous zones132
