Skip to main content
. 2021 May 31;12(6):563. doi: 10.1038/s41419-021-03843-0

Fig. 6. Loss of PBLD in IECs leads to excessive NF-κB activation in DSS-induced colitis.

Fig. 6

a Western blot analysis of proteins in IECs isolated from WT mice and PBLDIEC−/− mice treated with DSS for 5 days followed by 3 days regular drinking water. b qRT-PCR analysis of relative mRNA levels of genes in IECs isolated from WT mice and PBLDIEC−/− mice with DSS-induced colitis (n = 6). Data are mean ± standard deviation (SD). ***p < 0.001. c Immunoblotting analysis of proteins in primary IECs isolated from WT and PBLDIEC−/− mice after TNF-α treatment for 1 h.