Fig. 3.
Nucleotide and amino acid sequences of the functional VHDHJH regions. a Nucleotide and amino acid sequences of the functional HC V region. The chicken HC leader sequence, germline VH3-23, D5-12, and JH4 were linked directly without P/N nucleotides. The colored boxes indicate VH3-23 (green), D5-12 (purple) and JH4 (brown). b Nucleotide and amino acid sequences of the functional λ LC VJ region. The chicken LC leader sequence and VLJL region of Ramos cells were linked. The colored boxes indicate the corresponding germline V (IGLV2-14*01: blue) and J (IGLJ2*01: beige). c Nucleotide and amino acid sequences of the functional κ LC VLJL region. The frame regions were derived from the sequence obtained by linking Vκ 1-39 and Jκ2. The CDRs were human sequences derived from the database (protein IDs are indicated). The colored boxes indicate the corresponding germline V (Vκ 1-39: blue) and J (Jκ2: beige)