VOLUME 279 (2004) PAGES 11639–11648
This article has been withdrawn by the authors except Lianjun Yang who could not be reached. The Journal states that in Fig. 2B, the bands in the CCNL2 gel panel corresponding to CaoV-3 and HeLa were duplicated. In Fig. 2C, the bands in the β-actin panel on the left corresponding to ovary and small intestine were duplicated. The last two lanes in the PITSLRE p110 immunoblot in Fig. 4B were duplicated. The FACS plots in Fig. 6C for CCNL2-AS and mock present duplicated cells. In Fig. 8B, the bands corresponding to CCNL2-AS and mock in the Bax gel panel were duplicated.
The withdrawing authors state that they disagree with the Journal’s findings. This study was conducted nearly 20 years ago. The age of the work and the lack of availability of data storage makes it difficult for the authors to retrieve the requested raw data. The withdrawing authors’ offer to replace the images in question with those from other experiments under the same conditions was declined by the Journal. The withdrawing authors state that the above issues do not affect the interpretation of the data nor conclusions of this work. This article describes the discovery of novel molecule CCNL2 and characterizes its role in pre-mRNA splicing and tumor cell apoptosis induction. The withdrawing authors state that its function and mechanism have been confirmed by other independent studies. The withdrawing authors have indicated that they plan to resubmit their findings elsewhere for publication.
VOLUME 279 (2004) PAGES 11639–11648