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. 2020 Nov 23;28(5):1493–1511. doi: 10.1038/s41418-020-00677-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A, B Heatmaps SPAG5 and miR-10b-3p expression in METABRIC cohort (A) and in TCGA dataset (B). C, D Boxplot SPAG5 expression in tumoral versus normal breast tissues in METABRIC cohort (C) and in TCGA dataset (D). E, F Boxplot SPAG5 expression in Lum-A, Lum-B, Her2, and basal-like breast cancer histotypes in METABRIC cohort (E) and in the TCGA dataset (F). G, H Kaplan–Meier plots show survival analysis of breast cancer patients with low and high expression of SPAG5 in METABRIC cohort (G) and in the TCGA dataset (H).