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. 2021 May 31;11:11359. doi: 10.1038/s41598-021-90930-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Graphical representation of the results of two-way joining cluster analysis of the data on cytokine production by IC-NST samples and IC-NST histopathological parameters. (a) The horizontal axis of the graph shows the cytokines involved in the classification (according to their production by IC-NST samples, pg/ml), and the vertical axis indicates the encrypted numbers of IC-NST samples from different patients. (b) The graph shows horizontally the histopathological parameters involved in IC-NST classification, and vertically the encrypted numbers of IC–NST samples from different patients. The colors of the intersecting cells indicate that the matrix elements belong to a specific cluster. The color gradient from green to red respectively denotes an indicator’s value below or above the average.