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. 2021 May 31;11:11391. doi: 10.1038/s41598-021-90843-x

Table 2.

Association between %BF and protein levels in females and males for proteins with effect modification by sex.

Protein Females Males p-value interact p-value interact*
Coef 95% CI p-value Coef 95% CI p-value
CDCP1 0.43 0.33 to 0.53 < 0.001 0.58 0.48 to 0.67 < 0.001 0.264 0.027
GDNF − 0.21 − 0.31 to − 0.11 < 0.001 0.00 − 0.08 to 0.08 0.947 0.047 0.001
IL10 0.05 − 0.04 to 0.15 0.240 0.20 0.10 to 0.30 < 0.001 0.264 0.024
IL18R1 0.41 0.31 to 0.51 < 0.001 0.60 0.51 to 0.69 < 0.001 0.048 0.002
IL6 0.67 0.59 to 0.74 < 0.001 0.52 0.43 to 0.61 < 0.001 0.264 0.025
SCF − 0.09 − 0.19 to 0.00 0.064 − 0.31 − 0.41 to − 0.21 < 0.001 0.048 0.002

Stratified analyses in men and women from linear regression of transformed protein levels adjusted for smoking, e-cigarette use, snuff use, and age at follow-up.

The table includes all proteins with unadjusted p-value for the interaction term %BF#Sex of < 0.05.

p-values at 0.05 FDR.

*p-value for the interaction term without FDR correction.