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. 2021 May 31;11:11391. doi: 10.1038/s41598-021-90843-x

Table 3.

Association between %BF and protein levels stratified by BMI categories.

Protein Normal weight (18.5 to < 25 kg/m2) Overweight/ obesity (≥ 25 kg/m2) p-value interact p-value interact*
Coef 95% CI p-value Coef 95% CI p-value
CCL3 0.34 0.23 to 0.46 < 0.001 0.60 0.43 to 0.77 < 0.001 0.159 0.041
CCL20 0.09 − 0.03 to 0.20 0.232 0.37 0.19 to 0.55 < 0.001 0.120 0.023
CDCP1 0.27 0.16 to 0.38 < 0.001 0.88 0.71 to 1.05 < 0.001 0.005 < 0.001
DNER − 0.19 − 0.31 to − 0.08 0.007 − 0.30 − 0.47 to − 0.12 0.002 0.161 0.044
FGF21 0.30 0.19 to 0.42 < 0.001 0.74 0.58 to 0.91 < 0.001 0.111 0.019
FGF23 0.07 − 0.05 to 0.19 0.343 0.56 0.39 to 0.72 < 0.001 0.030 0.003
HGF 0.12 0.01 to 0.23 0.082 0.72 0.57 to 0.87 < 0.001 < 0.001 < 0.001
IL6 0.50 0.39 to 0.61 < 0.001 0.86 0.72 to 1.00 < 0.001 < 0.001 < 0.001
IL18 0.14 0.02 to 0.26 0.057 0.46 0.30 to 0.63 < 0.001 0.157 0.035
LAPTGFbeta1 − 0.03 − 0.14 to 0.09 0.733 0.33 0.15 to 0.50 0.001 0.032 0.004
MCP1 − 0.10 − 0.21 to 0.01 0.153 0.36 0.20 to 0.53 < 0.001 0.030 0.003
MCP4 − 0.08 − 0.20 to 0.04 0.255 0.27 0.11 to 0.44 0.003 0.005 < 0.001
OSM 0.02 − 0.10 to 0.13 0.843 0.35 0.18 to 0.52 < 0.001 0.111 0.018
TNFSF14 0.15 0.04 to 0.26 0.034 0.38 0.21 to 0.54 < 0.001 0.121 0.025

Stratified analyses in BMI categories from linear regression of transformed protein levels adjusted for sex, smoking, e-cigarette use, snuff use, and age at follow-up.

The table includes all proteins with unadjusted p-value for the interaction term %BF#BMI_category of < 0.05.

p-values at 0.05 FDR.

*p-value for the interaction term without FDR correction.