Table 2.
Clinical and pathological data of the patients enrolled in tissue and plasma study.
| Variable | Tissue study (n=28) | Plasma study (n=35) | P-value | Statistical test |
|---|---|---|---|---|
| Median (range) | Median (range) | |||
| Age (years) | 55.5 (36-84) | 60 (19-82) | 0.598 | Mann-Whitney U test |
| Body mass index | 25.6 (17.3-36.5) | 25.7 (18.4-40.4) | 0.682 | Mann-Whitney U test |
| n (%) | n (%) | |||
| Gender | ||||
| F | 12 (42.9%) | 13 (37.1%) | 0.796 | Fischer’s exact test |
| M | 16 (57.1%) | 22 (62.9%) | ||
| Tumor size | ||||
| T2 | 1 (3.6%) | 1 (2.9%) | 0.0174* | Fischer’s exact test |
| T3 | 22 (78.6%) | 16 (45.7%) | ||
| T4 | 5 (17.9%) | 16 (45.7%) | ||
| NA | – | 2 (5.7%) | ||
| Lymph nodes | ||||
| N0 | 3 (10.7%) | 6 (17.1%) | 0.566 | Fischer’s exact test |
| N1 | 14 (50.0%) | 12 (34.3%) | ||
| N2 | 11 (39.3%) | 13 (37.1%) | ||
| Nx | – | 4 (11.4%) | ||
| Metastasis | In evolution | Baseline | ||
| M-/M0 | 16 (57.1%) | 11 (31.4%) | – | – |
| M+/M1 | 12 (42.9%) | 22 (62.9%) | ||
| Mx | – | 2 (5.7%) | ||
| Lymphatic invasion | ||||
| L0 | 8 (28.6%) | 7 (20.0%) | 0.999 | Fischer’s exact test |
| L1 | 18 (64.3%) | 15 (42.9%) | ||
| Lx | 2 (7.1%) | 13 (37.1%) | ||
| Perineural invasion | ||||
| P0 | 16 (57.1%) | 11 (31.4%) | 0.524 | Fischer’s exact test |
| P1 | 7 (25.0%) | 8 (22.9%) | ||
| Px | 5 (17.9%) | 16 (45.7%) | ||
| Grade | ||||
| G1 | 5 (17.9%) | 4 (11.4%) | 0.926 | Fischer’s exact test |
| G2 | 18 (64.3%) | 19 (54.3%) | ||
| G3 | 5 (17.9%) | 5 (14.3%) | ||
| NA | – | 7 (20.0%) | ||
| Stage | ||||
| S2 | 3 (10.7%) | 4 (11.4%) | 0.168 | Fischer’s exact test |
| S3 | 25 (89.3%) | 8 (22.9%) | ||
| S4 | – | 23 (65.7%) | ||
*p≤0.05.