Table 5.
Significant differences between miRNAs with clinical data in the studied plasma samples.
| Variable | miR-17-5p P-value | miR-125b-5p P-value | miR-185-5p P-value | Statistical test |
|---|---|---|---|---|
|
Age
<50 vs. >50 |
0.418 | 0.324 | 0.809 | Mann Whitney |
|
Gender
M vs. F |
0.891 | 0.707 | 0.932 | Mann Whitney |
|
Tumor size
T3 vs. T4 |
0.157 | 0.146 | 0.317 | Mann Whitney |
|
Lymph nodes
N0 vs. N1 vs.N2 |
0.329 | 0.367 | 0.371 | Kruskal-Wallis |
|
Metastasis (baseline)
M0 vs. M1 |
0.339 | 0.163 | 0.479 | Mann Whitney |
|
Lymphatic invasion
L0 vs. L1 |
0.778 | 0.481 | 0.887 | Mann Whitney |
|
Perineural invasion
P0 vs. P1 |
0.772 | 0.265 | 0.710 | Mann Whitney |
|
Grade
G1 vs. G2 vs. G3 |
0.500 |
0.016*
(G2 vs.G3) |
0.393 | Kruskal-Wallis |
|
Stage
S2 vs. S3 vs. S4 |
0.396 |
0.046*
(S3 vs. S4) |
0.950 | Kruskal-Wallis |
*p≤0.05.