Fig. 2. Reagent synthesis and model reaction.

a Two-step synthesis procedure for the preparation of difluorinated allyl ammonium salts 1a–1e. b Optimization studies for the S_N2′ substitution reaction of difluoroallyl ammonium salt 1a with 4-phenyl phenol 2 in the presence of different basic conditions. ^†PdBr₂ (0.015 mmol) and ⁿBuPAd₂ (0.03 mmol) were used. ^‡The reaction was performed under an argon atmosphere.