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. 2021 May 31;12(6):560. doi: 10.1038/s41419-021-03830-5

Table 1.

List of potential autophagy inducers.

Compound Mean difference of mCit-LC3 (%) SD SSMD
P05E07 −34.4 ±6.0 −3.25
P02E06 −28.8 ±1.3 −12.58
P04C02 −27.4 ±5.6 −2.75
P01F03 −22.0 ±11.2 −1.11
P05C06 −19.9 ±4.6 −2.43
P01G08 −18.1 ±8.1 −1.26
P03F08 −17.7 ±3.3 −3.04
P02B03 −17.3 ±6.0 −1.62

SD standard deviation SSMD strictly standardized mean difference.

In total, eight compounds causing equal to or greater than 15% LC3 degradation at a fairly moderate and higher effect (│SSMD score│ ≥1) at 10 µM after 6 h of treatment were classified as potential inducers of autophagy.

Data show mean difference ± SD (% of control) of mCitrine-LC3 decrease upon full medium monitored by flow cytometry.