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. 2020 Oct 9;18(6):1437–1449. doi: 10.1038/s41423-020-00559-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Comparative transcriptomic analysis of BLT1^hi and BLT1^lo DCs. a Venn diagrams show genes highly expressed in BLT1^hi DCs (left) and BLT1^lo DCs (right) under various conditions (exposure to LPS [100 ng/ml] and CpG DNA [1 μM] treatment for 4 h). Gene Ontology (GO) analysis was performed on 574 genes highly expressed in BLT1^hi DCs (b) and on 404 genes highly expressed in BLT1^lo DCs (c). The top 5 GO terms are listed. The numbers indicate the number of genes categorized in that GO term (574 genes (b) or 404 genes (c)). d The 231 genes listed in the top 5 GO terms for BLT1^hi DCs and the 95 genes listed in the top 5 GO terms for BLT1^lo DCs were categorized as follows: cytokines, transcription factors (TFs), CD antigens, receptors, and other. A heat map is shown. V, vehicle-treated group; L, LPS-treated group; C, CpG DNA-treated group