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. 2021 Jun 1;8:124. doi: 10.1038/s41438-021-00561-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a The numbers of up- and downregulated DEGs in Pb200 vs Control, Pb_50MT vs Control, and Pb_50MT vs Pb200. b The expression patterns of Pb200 vs Control downregulated and Pb_50MT vs Pb200 upregulated DEGs. c The overlapping DEGs between Pb200 vs Control and Pb_50MT vs Control. d The overlapping DEGs between Pb200 vs Control and Pb_50MT vs Pb200. e, f The expression patterns of overlapped DEGs. g, h Correlation of differential methylation levels of overlapping DEGs