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CaBLAM outliers to flag problems at 2.5 to 4 Å, applied to SARS-CoV-2 structures.A, original model of a loop in Nsp8 of the 7bv2 RNA-dependent RNA polymerase structure, with two adjacent CaBLAM outliers and only three H-bonds. B, with a large reorientation of the central peptide of those outliers, this loop forms a near-ideal β-hairpin with seven H-bonds including two to an adjacent chain in the complex (7bv2 v2.0).
